P939Chronic hypoxia-induced CIRP hypermethylation attenuates hypothermic cardioprotection during cardiopulmonary bypass
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منابع مشابه
Cerebral Artery During Nonpulsatile Hypothermic Cardiopulmonary Bypass
Background and Purpose We evaluated the utility of blood flow velocity measurements by transcranial Doppler ultrasonography as a tool to indirectly measure cerebral perfusion during cardiopulmonary bypass. Methods We simultaneously measured blood flow velocity in the middle cerebral artery and physiological variables in 18 patients undergoing cardiac surgery under hypothermic cardiopulmonary by...
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The hemoglobin P 50 was ascertained prior to anesthesia and CPB and calculated during hypothermic CPB to track the change in hemoglobin affinity in fifty randomly selected cardiac disease patients. The AMINCO Hem-0-Scan standardized P50 averaged 32.1 +16.8 (1 SD) mmHg in the awake, slightly sedated CPB candidate. The awake patients were distributed into three significantly different (p < .05) g...
متن کاملHypothermic Cardiopulmonary Bypass
Background and Purpose We evaluated the utility of blood flow velocity measurements by transcranial Doppler ultrasonography as a tool to indirectly measure cerebral perfusion during cardiopulmonary bypass. Methods We simultaneously measured blood flow velocity in the middle cerebral artery and physiological variables in 18 patients undergoing cardiac surgery under hypothermic cardiopulmonary by...
متن کاملPharmacokinetics of doxacurium during normothermic and hypothermic cardiopulmonary bypass surgery.
PURPOSE To compare the pharmacokinetic behaviour of doxacurium in patients undergoing normothermic or hypothermic cardiopulmonary bypass (CPB) for coronary artery bypass graft surgery. METHODS Twenty patients in two equal groups were studied. Anaesthesia was induced with sufentanil and midazolam after a standard premedication. Doxacurium was administered at 3 x ED95 (80 micrograms.kg-1), and ...
متن کاملMyocardial Preservation during Hypothermic Cardiopulmonary Bypass: A Team Endeavor
____________ _ Myocardial failure is the primary cause of death following operation using hypothermic cardiopulmonary bypass. The mean mortality rate for coronary bypass in Medicare patients in the United States for 1984 was 5.5%.1njury to the heart is caused by aortic cross-clamping or total circulatory arrest. The lesion of hypoxia is characterized by progressive acidosis. The severity of aci...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2018
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehy564.p939